上海埃飛科技
Worldwide Technology(S. H)產品展示
磁熱療設備
加熱納米顆粒已經證明是一種消融腫瘤的手段,對42-45C的癌細胞做進一步的化療可以使癌細胞死亡。指定的溫度相應磁脂質體被用來對腫瘤組織直接釋放癌癥藥物。
產品簡介:
加熱納米顆粒已經證明是一種消融腫瘤的手段,對42-45C的癌細胞做進一步的化療可以使癌細胞死亡。指定的溫度相應磁脂質體被用來對腫瘤組織直接釋放癌癥藥物。
磁熱療和化療有著顯著的協同作用。(1)削弱癌細胞對藥物的抵抗。(2)改善滲透率和腫瘤組織微血管孔徑。(3)高效、精確地投遞癌癥藥物,減少藥物的系統性毒性
MSI 磁流體熱療系統技術特征:
√ 磁功率強度:最高可達80坎普/米
√ 用于納米顆粒研究的加熱線圈尺寸:40-80毫米,用于動物研究的加熱線圈尺寸:90-120毫米
√ neoptix光纖溫度傳感器系統更多復雜且多方面測量的方案
磁熱療是一種相對新的理念和癌癥治療手段?,F在有兩種治療方法正在測試。在腫瘤組織內注射納米顆粒,加熱至42-45C,使腫瘤細胞消融,崩潰,出血。另一個方法是用溫度相應的磁脂質體瞄準腫瘤組織。磁加引發化療藥物釋放,通常配合核磁共振成像來觀察腫瘤組織內脂質體的濃度。而且加熱進一步提高藥物在腫瘤組織血管內的滲透率,提高整體治療療效。
技術原理:
磁熱療手段已經吸引了世界范圍的興趣,首先被用于大學和藥物研究實驗室中,它利用交變電流產生交變磁場,利用磁性納米顆粒在交變磁場中做無序運動從而產生熱能。目前小動物測試已經取得了很大成功。最近,改進MSI自動系統的磁熱的能量已經給研究者帶來了新的機會。過去,所有的研究幾乎都只針對小白鼠?,F在MSI系統已經通過增加到120mm的線圈直徑,可以提供更高的的磁熱能。MSI自動系統正在推動其他創新 ,把磁熱療技術推向臨床試驗。
應用領域:
?小動物腫瘤治愈
?腫瘤細胞研究
?磁性納米顆粒合成
?藥劑學
?熱休克蛋白
?藥物釋放
?藥理&生化學家
應用案例
兔子喬治:我們正在治療骨癌,一種在很多國家很常見的癌癥。研究成果將會同比例放大、跟進到人類大小的線圈。
Product introduction:
Heating nanoparticles has proven to be a means to ablate tumors, and further chemotherapy for 42-45C cancer cells can kill cancer cells. The magnetic liposome corresponding to the specified temperature is used to directly release cancer drugs to the tumor tissue.
Magnetic hyperthermia and chemotherapy have a significant synergistic effect. (1) Weaken the resistance of cancer cells to drugs. (2) Improve permeability and pore size of tumor tissue microvessels. (3) Efficient and precise delivery of cancer drugs, reducing the systemic toxicity of drugs
Technical characteristics of MSI magnetic fluid hyperthermia system:
√ Magnetic power intensity: up to 80 camp/m
√ Heating coil size for nanoparticle research: 40-80 mm, heating coil size for animal research: 90-120 mm
√ More complex and multi-faceted measurement solutions for neoptix optical fiber temperature sensor system
Magnetic hyperthermia is a relatively new concept and cancer treatment method. Two treatments are currently being tested. Nanoparticles are injected into the tumor tissue and heated to 42-45C to cause the tumor cells to ablate, collapse and bleed. Another method is to target the tumor tissue with magnetic liposomes corresponding to the temperature. Magnetism triggers the release of chemotherapeutic drugs, usually with MRI to observe the concentration of liposomes in tumor tissues. Moreover, heating further increases the penetration rate of the drug in the blood vessel of the tumor tissue and improves the overall therapeutic effect.
Technical principle:
Magnetic hyperthermia has attracted worldwide interest. It was first used in universities and pharmaceutical research laboratories. It uses alternating current to generate an alternating magnetic field, and uses magnetic nanoparticles to move disorderly in an alternating magnetic field to generate heat. . At present, small animal testing has achieved great success. Recently, improving the magneto-caloric energy of the MSI automatic system has brought new opportunities to researchers. In the past, almost all studies have focused on mice. Now the MSI system has increased the coil diameter to 120mm, which can provide higher magnetocaloric energy. The MSI automated system is driving other innovations, pushing magnetic hyperthermia technology into clinical trials.
Application areas:
? Small animal tumors are cured
? Tumor cell research
? Synthesis of magnetic nanoparticles
? Pharmacy
? Heat shock protein
? Drug release
? Pharmacologist & Biochemist
Applications
George Rabbit: We are treating bone cancer, a cancer that is very common in many countries. The research results will be scaled up and followed up to human-sized coils.
因用于機器人各方面應用且與大多數機器人類型兼容,AutoCal系統可以檢測出機器人自身構造和工具中心點(TCP)的 突然改變或偏離,并且該系統無需人為干涉就自動地更正這些誤差。
AutoCal系統-Dynalog的先進水平校準技術,Dynalog是機器人單元標定技術的世界領導者。它的主流產品DynaCal 系統,被應用于離線的機器人單元校準,并作為最精確的和技術先進的機器人校準程序為許多機器人制造商和終端使用者所接受。AutoCal 系統將已證實的DynaCal校準技術結合到一個在線的全自動系統中,該系統專為程序控制和復原而設計的,價格低廉。
AutoCal系統提供在線的機器人校準方案,旨在快速和自動地保證機械設備的工作性能。因用于機器人各方面應用且與大多數機器人類型兼容,AutoCal系統可以檢測出機器人自身構造和工具中心點(TCP)的 突然改變或偏離,并且該系統無需人為干涉就自動地更正這些誤差。這意味著不用猜測哪里會出錯,不用浪費寶貴時間在機器人程序重復校準上,產品品質無任何損失。
AutoCal系統-Dynalog的先進水平校準技術,Dynalog是機器人單元標定技術的世界領導者。它的主流產品DynaCal 系統,被應用于離線的機器人單元校準,并作為最精確的和技術先進的機器人校準程序為許多機器人制造商和終端使用者所接受。AutoCal 系統將已證實的DynaCal校準技術結合到一個在線的全自動系統中,該系統專為程序控制和復原而設計的,價格低廉。